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Term Information

Accession
GO:1990922
Name
hepatic stellate cell proliferation
Ontology
biological_process
Synonyms
Ito cell proliferation, hepatic perisinusoidal cell proliferation, perisinusoidal cell proliferation
Alternate IDs
None
Definition
The multiplication or reproduction of hepatic stellate cells, resulting in the expansion of a hepatic stellate cell population. Hepatic stellate cells are found in the perisinusoidal space of the liver, and are capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components. This cell type comprises approximately 8-15% of total cells in the liver. Source: PMID:15358192, PMID:18466260, GOC:sl
Comment
None
History
See term history for GO:1990922 at QuickGO
Subset
None
Feedback
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Graph of GO:1990922

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Parents of hepatic stellate cell proliferation (GO:1990922)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
hepatic stellate cell proliferation [is_a relation] is_a  fibroblast proliferation (GO:0048144)
Children of hepatic stellate cell proliferation (GO:1990922)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of hepatic stellate cell proliferation (GO:1904898) [RO:0002212 relation] RO:0002212  hepatic stellate cell proliferation
regulation of hepatic stellate cell proliferation (GO:1904897) [RO:0002211 relation] RO:0002211  hepatic stellate cell proliferation
positive regulation of hepatic stellate cell proliferation (GO:1904899) [RO:0002213 relation] RO:0002213  hepatic stellate cell proliferation
None.