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Term Information

Accession
GO:1990733
Name
titin-telethonin complex
Ontology
cellular_component
Synonyms
Titin-Tcap complex
Alternate IDs
None
Definition
A protein complex formed between the N-terminus of the giant sarcomeric filament protein titin and the Z-disk ligand, telethonin. The complex is part of the Z-disk of the skeletal and cardiac sarcomere. Telethonin binding to titin might be essential for the initial assembly, stabilization and functional integrity of the titin filament, and hence important for muscle contraction relaxation in mature myofibrils. Source: GOC:ame, PMID:16407954
Comment
An example of this are TTN and TCAP in human (UniProt symbols Q8WZ42 and O15273 respectively) in PMID:16407954 (inferred from direct assay).
History
See term history for GO:1990733 at QuickGO
Subset
None
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Graph of GO:1990733

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Parents of titin-telethonin complex (GO:1990733)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
titin-telethonin complex [BFO:0000050 relation] BFO:0000050  Z disc (GO:0030018)
titin-telethonin complex [is_a relation] is_a  protein-containing complex (GO:0032991)

This term has no children.

IntAct
EBI-10711453