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Term Information

Accession
GO:1990684
Name
protein-lipid-RNA complex
Ontology
cellular_component
Synonyms
miRNA-lipoprotein complex
Alternate IDs
None
Definition
A macromolecular complex containing separate protein, lipid and RNA molecules. Separate in this context means not covalently bound to each other. Source: GOC:vesicles, PMID:21423178, PMID:23559634, PMID:22028337
Comment
Examples of protein-lipid-RNA complexes are described in PMID:21423178 and PMID:23559634, both showing evidence that high-density lipoprotein (HDL) and, to a lesser extent, low-density lipoprotein (HDL) transport endogenous microRNAs (miRNAs) and deliver them to recipient cells with functional targeting capabilities. Also see fig. 1 in the review PMID:22028337. Not to be confused with GO:0034364 'high-density lipoprotein particle' or GO:0034362 'low-density lipoprotein particle', which describe complexes of proteins and lipids only, without RNAs.
History
See term history for GO:1990684 at QuickGO
Subset
None
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Graph of GO:1990684

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Parents of protein-lipid-RNA complex (GO:1990684)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
protein-lipid-RNA complex [is_a relation] is_a  protein-containing complex (GO:0032991)
Children of protein-lipid-RNA complex (GO:1990684)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
LDL-containing protein-lipid-RNA complex (GO:1990686) [is_a relation] is_a  protein-lipid-RNA complex
HDL-containing protein-lipid-RNA complex (GO:1990685) [is_a relation] is_a  protein-lipid-RNA complex
None.