You are using the Cyverse mirror of the Planteome Ontology Browser. The main site is at browser.planteome.org.

Term Information

Accession
GO:1990302
Name
Bre1-Rad6 ubiquitin ligase complex
Ontology
cellular_component
Synonyms
Bre1-Rad6 complex
Alternate IDs
None
Definition
A ubiquitin ligase complex consisting of Bre1 and Rad6 that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. It thereby plays a central role in histone code and gene regulation. It also modulates the formation of double-strand breaks during meiosis. Source: PMID:19531475, GOC:bhm
Comment
This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:19531475 (inferred from direct assay).
History
See term history for GO:1990302 at QuickGO
Subset
None
Feedback
Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
External term view.

Graph of GO:1990302

Viewing options
Parents of Bre1-Rad6 ubiquitin ligase complex (GO:1990302)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
Bre1-Rad6 ubiquitin ligase complex [is_a relation] is_a  transferase complex (GO:1990234)
Bre1-Rad6 ubiquitin ligase complex [BFO:0000050 relation] BFO:0000050  intracellular anatomical structure (GO:0005622)

This term has no children.

IntAct
EBI-9102228