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Term Information

Accession
GO:1990130
Name
GATOR1 complex
Ontology
cellular_component
Synonyms
IML1 complex, SEACIT complex
Alternate IDs
None
Definition
A GTPase-activating protein (GAP) complex that regulates TORC1 signaling by interacting with the Rag GTPase. In human, the GATOR1 complex consists of DEPDC5, NPRL2, and NPRL3. In S. cerevisiae, this complex is referred to as SEACIT and contains the Iml1p, Npr2p, and Npr3p proteins. Source: GOC:krc, PMID:21900499, PMID:29199950, GOC:rb, PMID:23974112, PMID:28199306, PMID:23723238, PMID:25934700
Comment
The Rag GTPase complex corresponds to Gtr1-Gtr2 GTPase complex ; GO:1990131.
History
See term history for GO:1990130 at QuickGO
Subset
None
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Graph of GO:1990130

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Parents of GATOR1 complex (GO:1990130)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
GATOR1 complex [BFO:0000050 relation] BFO:0000050  Seh1-associated complex (GO:0035859)
GATOR1 complex [is_a relation] is_a  protein-containing complex (GO:0032991)

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None.