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Term Information

Accession
GO:1904091
Name
peptidyl carrier protein activity
Ontology
molecular_function
Synonyms
oligopeptide binding involved in non-ribosomal peptide biosynthesis, oligopeptide binding involved in non-ribosomal peptide biosynthetic process, oligopeptide binding involved in non-ribosomal peptide formation, oligopeptide binding involved in non-ribosomal peptide synthesis, oligopeptide binding involved in nonribosomal peptide anabolism, oligopeptide binding involved in nonribosomal peptide biosynthesis, oligopeptide binding involved in nonribosomal peptide biosynthetic process, oligopeptide binding involved in nonribosomal peptide formation, oligopeptide binding involved in nonribosomal peptide synthesis, oligopeptides binding involved in non-ribosomal peptide biosynthesis, oligopeptides binding involved in non-ribosomal peptide biosynthetic process, oligopeptides binding involved in non-ribosomal peptide formation, oligopeptides binding involved in non-ribosomal peptide synthesis, oligopeptides binding involved in nonribosomal peptide anabolism, oligopeptides binding involved in nonribosomal peptide biosynthesis, oligopeptides binding involved in nonribosomal peptide biosynthetic process, oligopeptides binding involved in nonribosomal peptide formation, oligopeptides binding involved in nonribosomal peptide synthesis, peptidyl binding involved in nonribosomal peptide biosynthesis, peptidyl binding involved in nonribosomal peptide biosynthetic process, peptidyl carrier protein activity involved in nonribosomal peptide biosynthesis, peptidyl carrier protein activity involved in nonribosomal peptide biosynthetic process, Oligopeptid binding involved in non-ribosomal peptide biosynthesis, Oligopeptid binding involved in non-ribosomal peptide biosynthetic process, Oligopeptid binding involved in non-ribosomal peptide formation, Oligopeptid binding involved in non-ribosomal peptide synthesis, Oligopeptid binding involved in nonribosomal peptide anabolism, Oligopeptid binding involved in nonribosomal peptide biosynthesis, Oligopeptid binding involved in nonribosomal peptide biosynthetic process, Oligopeptid binding involved in nonribosomal peptide formation, Oligopeptid binding involved in nonribosomal peptide synthesis, Oligopeptid binding involved in nonribosomal peptide synthetase, PCP, oligopeptide binding involved in nonribosomal peptide synthetase, oligopeptides binding involved in nonribosomal peptide synthetase, oligopeptido binding involved in non-ribosomal peptide biosynthesis, oligopeptido binding involved in non-ribosomal peptide biosynthetic process, oligopeptido binding involved in non-ribosomal peptide formation, oligopeptido binding involved in non-ribosomal peptide synthesis, oligopeptido binding involved in nonribosomal peptide anabolism, oligopeptido binding involved in nonribosomal peptide biosynthesis, oligopeptido binding involved in nonribosomal peptide biosynthetic process, oligopeptido binding involved in nonribosomal peptide formation, oligopeptido binding involved in nonribosomal peptide synthesis, oligopeptido binding involved in nonribosomal peptide synthetase, peptidyl carrier protein
Alternate IDs
None
Definition
Binding an amino-acid derived peptidyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the peptidyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. Peptidyl carrier protein (PCP) is involved in nonribosomal peptide biosynthetic process. Source: GO_REF:0000061, PMID:17502372, GOC:TermGenie, GOC:pr, GOC:vw
Comment
Examples are the ferrichrome synthetase Sib1 in S. pombe and the peptidyl carrier protein (PCP) module in bacterial nonribosomal peptide synthases (NRPSs), which holds the peptidyl group and acts as a swinging arm, limiting diffusion until the peptide comes into contact with the next enzymatic module in the NRPS process.
History
See term history for GO:1904091 at QuickGO
Subset
None
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Graph of GO:1904091

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Parents of peptidyl carrier protein activity (GO:1904091)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
peptidyl carrier protein activity [is_a relation] is_a  phosphopantetheine-dependent carrier activity (GO:0140414)
peptidyl carrier protein activity [BFO:0000050 relation] BFO:0000050  nonribosomal peptide biosynthetic process (GO:0019184)

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