Planteome: Term Details for "PAR polarity complex" (GO:0120157)

You are using the Cyverse mirror of the Planteome Ontology Browser. The main site is at browser.planteome.org.

Notice

Some functionality on this page depends on JavaScript. To fully use the features of AmiGO 2, enable JavaScript in your browser and reload from the landing page.

Term Information

Accession: GO:0120157
Name: PAR polarity complex
Ontology: cellular_component
Synonyms: apical polarity complex, BEM1-CDC24-CLA4 complex, Cdc42p GEF-PAK complex, PAR3-PAR6-atypical PKC, PAR3/PAR6/aPKC, PAR6-PAR3-aPKC complex
Alternate IDs: None
Definition: A protein kinase complex that is required for the establishment of a cell polarity axis during the cell division cycle. Binds directly to activated CDC42 GTPase and is required for orchestrating a cellular gradient of CDC42. In S. cerevisiae components are: BEM1, CDC24 and CLA4; from worms to vertebrates it contains a PAR6 protein, PAR3 protein and an atypical PKC. Source: PMID:18005931, PMID:28682236, GOC:lnp, PMID:11113154, PMID:22500799
Comment: "This tripartite complex named PAR6/PAR3/aPKC is conserved from worms to vertebrates" (PMID:18005931). In yeast, the components are BEM1, CDC24, and CLA4.
History: See term history for GO:0120157 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to PAR polarity complex.; Link to all direct and indirect annotations to PAR polarity complex.; Link to all direct and indirect annotations download (limited to first 10,000) for PAR polarity complex.
Feedback: Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.