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Term Information

Accession
GO:0120123
Name
ubiquitin activating enzyme complex
Ontology
cellular_component
Synonyms
E1 complex, E1 ubiquitin-activating enzyme
Alternate IDs
None
Definition
A protein complex responsible for the catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate. Source: GOC:lnp, PMID:9545234
Comment
None
History
See term history for GO:0120123 at QuickGO
Subset
None
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Graph of GO:0120123

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Parents of ubiquitin activating enzyme complex (GO:0120123)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ubiquitin activating enzyme complex [BFO:0000050 relation] BFO:0000050  intracellular anatomical structure (GO:0005622)
ubiquitin activating enzyme complex [is_a relation] is_a  catalytic complex (GO:1902494)

This term has no children.

IntAct
EBI-16629455