Planteome: Term Details for "B-WICH complex" (GO:0110016)

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Term Information

Accession: GO:0110016
Name: B-WICH complex
Ontology: cellular_component
Synonyms: None
Alternate IDs: None
Definition: A chromatin remodeling complex that positively regulates histone H3 acetylation, in particular H3K9, by recruiting histone acetyltransferases to rDNA gene regions. Located in the nucleolus where it assembles on RNA Polymerase I (Pol I) and possibly on RNA Polymerase III (Pol III) promoter and coding regions during early G1 phase and activates the post-initiation phases of Pol I transcription. May also activate RNA Polymerase II (Pol II) gene transcription. In mammals, B-WICH contains the WICH complex core of BAZ1B and SMARCA5, additional protein subunits and possibly rRNAs. Although it contains several catalytic subunits it is not clear which functions are carried out by the complex itself. Source: PMID:21559432, PMID:16603771, PMID:26044184, PMID:23555303, GOC:bhm
Comment: An example is BAZ1B (Q9UIG0) in human in PMID:16603771 (by IPI).
History: See term history for GO:0110016 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to B-WICH complex.; Link to all direct and indirect annotations to B-WICH complex.; Link to all direct and indirect annotations download (limited to first 10,000) for B-WICH complex.
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