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resolution phase response
Term Information
Accession
GO:0106299
Name
resolution phase response
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
An active host response phase of acute inflammation driven by specialized pro-resolving mediators (SPMs) and signaling pathways, enabling timely tissue regeneration and return of function.
Source:PMID:28087575
Comment
Acute inflammatory response(s) are self-limited, resolve on their own and classically divide into initiation and resolution phases. SPMs are a superfamily of proresolving mediators that include resolvins (Rvs), protectins (PDs), maresins (MaRs) and lipoxins (LXs).
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