Planteome: Term Details for "mCRD-mediated mRNA stability complex" (GO:0106002)

Term Information

Accession: GO:0106002
Name: mCRD-mediated mRNA stability complex
Ontology: cellular_component
Synonyms: mCRD-poly(A)-bridging complex, major coding region determinant of instability-mediated mRNA stability complex, major coding region instability determinant-mediated mRNA stability complex, major coding region instability determinant-poly(A)-bridging complex, major coding-region determinant of instability - poly(A) tail-bridging complex
Alternate IDs: None
Definition: A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the major coding region instability determinant (mCRD) by bridging the mCRD domain and the poly(A) tail of the mRNA. In human, it consists of CSDE1, HNRPD, PABPC1, PAIP1 and SYNCRIP. Source: PMID:11051545, GOC:bhm
Comment: This complex is related to GO:0070937 CRD-mediated mRNA stability complex but binds the major protein-coding-region determinant of instability (mCRD) domain rather than the CRD. Experimentally it has been shown to act on c-FOS mRNA while GO:0070937 acts on c-MYC mRNA.
History: See term history for GO:0106002 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to mCRD-mediated mRNA stability complex.; Link to all direct and indirect annotations to mCRD-mediated mRNA stability complex.; Link to all direct and indirect annotations download (limited to first 10,000) for mCRD-mediated mRNA stability complex.
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