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Term Information

Accession
GO:0097619
Name
PTEX complex
Ontology
cellular_component
Synonyms
Plasmodium translocon of exported proteins
Alternate IDs
None
Definition
A protein complex that acts as a protein trafficking machinery and is responsible for the export of proteins across the parasitophorous (symbiont-containing) vacuolar membrane and into the human host cell. The PTEX complex is located in the vacuole membrane. It is ATP-powered, and comprises heat shock protein 101 (HSP101; a ClpA/B-like ATPase from the AAA+ superfamily, of a type commonly associated with protein translocons), a parasite protein termed PTEX150, and exported protein 2 (EXP2). EXP2 is the potential channel, as it is the membrane-associated component of the core PTEX complex. Two other proteins, PTEX88 and thioredoxin 2 (TRX2), were also identified as PTEX components. Source: GOC:pr, PMID:25043010, PMID:25043043, PMID:19536257
Comment
None
History
See term history for GO:0097619 at QuickGO
Subset
None
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Graph of GO:0097619

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Parents of PTEX complex (GO:0097619)
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PTEX complex [is_a relation] is_a  protein-containing complex (GO:0032991)
PTEX complex [BFO:0000050 relation] BFO:0000050  symbiont-containing vacuole membrane (GO:0020005)

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