You are using the Cyverse mirror of the Planteome Ontology Browser. The main site is at browser.planteome.org.

Term Information

Accession
GO:0097411
Name
hypoxia-inducible factor-1alpha signaling pathway
Ontology
biological_process
Synonyms
HIF1alpha pathway, hypoxia-inducible factor signaling, hypoxia-inducible factor-1alpha signalling pathway
Alternate IDs
None
Definition
A series of molecular signals mediated by hypoxia-inducible factor (HIF1) in response to lowered oxygen levels (hypoxia). Under hypoxic conditions, the oxygen-sensitive alpha-subunit of hypoxia-inducible factor (HIF)-1 dimerizes with a HIF1-beta subunit (also called ARNT or aryl-hydrocarbon-receptor nuclear translocator), translocates to the nucleus and activates transcription of genes whose products participate in responding to hypoxia. Source: GOC:bf, http://www.sabiosciences.com/pathway.php?sn=HIF1Alpha_Pathway, GOC:jc
Comment
None
History
See term history for GO:0097411 at QuickGO
Subset
None
Feedback
Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
External term view.

Graph of GO:0097411

Viewing options
Parents of hypoxia-inducible factor-1alpha signaling pathway (GO:0097411)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
hypoxia-inducible factor-1alpha signaling pathway [is_a relation] is_a  signal transduction (GO:0007165)
hypoxia-inducible factor-1alpha signaling pathway [BFO:0000050 relation] BFO:0000050  cellular response to hypoxia (GO:0071456)
Children of hypoxia-inducible factor-1alpha signaling pathway (GO:0097411)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of hypoxia-inducible factor-1alpha signaling pathway (GO:1902072) [RO:0002212 relation] RO:0002212  hypoxia-inducible factor-1alpha signaling pathway
positive regulation of hypoxia-inducible factor-1alpha signaling pathway (GO:1902073) [RO:0002213 relation] RO:0002213  hypoxia-inducible factor-1alpha signaling pathway
regulation of hypoxia-inducible factor-1alpha signaling pathway (GO:1902071) [RO:0002211 relation] RO:0002211  hypoxia-inducible factor-1alpha signaling pathway
None.