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mature conventional dendritic cell differentiation

Term Information

Accession
GO:0097029
Name
mature conventional dendritic cell differentiation
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells. Source: PMID:15845453, http://www.rndsystems.com/mini_review_detail_objectname_MR02_DendriticCellMat.aspx, GOC:BHF
Comment
Note that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'.
History
See term history for GO:0097029 at QuickGO
Subset
None
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Graph of GO:0097029

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Parents of mature conventional dendritic cell differentiation (GO:0097029)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
mature conventional dendritic cell differentiation [is_a relation] is_a  dendritic cell differentiation (GO:0097028)
mature conventional dendritic cell differentiation [is_a relation] is_a  myeloid leukocyte differentiation (GO:0002573)

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