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Term Information

Accession
GO:0090394
Name
negative regulation of excitatory postsynaptic potential
Ontology
biological_process
Synonyms
negative regulation of excitatory post-synaptic membrane potential, reduction of excitatory postsynaptic membrane potential, negative regulation of EPSP
Alternate IDs
None
Definition
Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. Source: GOC:BHF
Comment
None
History
See term history for GO:0090394 at QuickGO
Subset
None
Feedback
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Graph of GO:0090394

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Parents of negative regulation of excitatory postsynaptic potential (GO:0090394)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of excitatory postsynaptic potential [RO:0002212 relation] RO:0002212  excitatory postsynaptic potential (GO:0060079)
negative regulation of excitatory postsynaptic potential [is_a relation] is_a  negative regulation of signal transduction (GO:0009968)
negative regulation of excitatory postsynaptic potential [is_a relation] is_a  negative regulation of synaptic transmission (GO:0050805)
negative regulation of excitatory postsynaptic potential [is_a relation] is_a  modulation of excitatory postsynaptic potential (GO:0098815)
Children of negative regulation of excitatory postsynaptic potential (GO:0090394)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of mini excitatory postsynaptic potential (GO:0061886) [is_a relation] is_a  negative regulation of excitatory postsynaptic potential
None.