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Term Information

Accession
GO:0090200
Name
positive regulation of release of cytochrome c from mitochondria
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation. Source: GOC:dph, GOC:tb, GOC:BHF, GOC:mtg_apoptosis
Comment
The release of cytochrome c from mitochondria is a central event in the signaling phase of the apoptotic process, and it is often used by researchers to monitor this type of cell death. Any event that induces apoptosis will at some point induce the release of cytochrome c from mitochondria. Therefore, this term should only be used to annotate gene products that directly and positively regulate this process.
History
See term history for GO:0090200 at QuickGO
Subset
None
Feedback
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Graph of GO:0090200

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Parents of positive regulation of release of cytochrome c from mitochondria (GO:0090200)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of release of cytochrome c from mitochondria [is_a relation] is_a  regulation of release of cytochrome c from mitochondria (GO:0090199)
positive regulation of release of cytochrome c from mitochondria [RO:0002213 relation] RO:0002213  release of cytochrome c from mitochondria (GO:0001836)
positive regulation of release of cytochrome c from mitochondria [is_a relation] is_a  positive regulation of mitochondrion organization (GO:0010822)

This term has no children.

None.