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Term Information

Accession
GO:0090090
Name
negative regulation of canonical Wnt signaling pathway
Ontology
biological_process
Synonyms
negative regulation of Wnt receptor signaling pathway through beta-catenin, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of canonical Wnt receptor signalling pathway, negative regulation of canonical Wnt-activated signaling pathway, negative regulation of catenin import into nucleus, negative regulation of catenin protein nuclear translocation
Alternate IDs
GO:0035414
Definition
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. Source: GOC:dph, GOC:tb
Comment
None
History
See term history for GO:0090090 at QuickGO
Subset
None
Feedback
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Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Graph of GO:0090090

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Parents of negative regulation of canonical Wnt signaling pathway (GO:0090090)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of canonical Wnt signaling pathway [is_a relation] is_a  regulation of canonical Wnt signaling pathway (GO:0060828)
negative regulation of canonical Wnt signaling pathway [is_a relation] is_a  negative regulation of Wnt signaling pathway (GO:0030178)
negative regulation of canonical Wnt signaling pathway [RO:0002212 relation] RO:0002212  canonical Wnt signaling pathway (GO:0060070)
Children of negative regulation of canonical Wnt signaling pathway (GO:0090090)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway (GO:1902844) [is_a relation] is_a  negative regulation of canonical Wnt signaling pathway
negative regulation of canonical Wnt signaling pathway involved in heart development (GO:1905067) [is_a relation] is_a  negative regulation of canonical Wnt signaling pathway
positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway (GO:0090082) [is_a relation] is_a  negative regulation of canonical Wnt signaling pathway
negative regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation (GO:0072336) [is_a relation] is_a  negative regulation of canonical Wnt signaling pathway
negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation (GO:1905240) [is_a relation] is_a  negative regulation of canonical Wnt signaling pathway
negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation (GO:2000080) [is_a relation] is_a  negative regulation of canonical Wnt signaling pathway
negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation (GO:0060829) [is_a relation] is_a  negative regulation of canonical Wnt signaling pathway
None.