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Term Information

Accession
GO:0086096
Name
adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process
Ontology
biological_process
Synonyms
G-inhibitory-coupled Beta2AR signaling pathway involved in heart process, Gi-coupled Beta2-AR signaling pathway involved in heart process, Gi-coupled adrenergic receptor signaling pathway involved in heart process, cardiac adrenergic receptor signaling pathway via inhibition of adenylate cyclase activity
Alternate IDs
None
Definition
An adrenergic receptor signaling pathway which contributes to a circulatory system process carried out by the heart, where the activated adrenergic receptor transmits the signal by Gi-mediated inhibition of adenylate cyclase activity. Source: GOC:BHF, PMID:10571541, GOC:mtg_cardiac_conduct_nov11
Comment
Although Beta1-adrenergic receptors couple exclusively to the Gs protein, Beta2-adrenergic receptors couple to both Gs and Gi proteins. Coupling to Gi proteins may localize the Gs-mediated signaling.
History
See term history for GO:0086096 at QuickGO
Subset
None
Feedback
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Graph of GO:0086096

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Parents of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process (GO:0086096)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process [is_a relation] is_a  adenylate cyclase-inhibiting adrenergic receptor signaling pathway (GO:0071881)
adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process [is_a relation] is_a  G protein-coupled receptor signaling pathway involved in heart process (GO:0086103)
adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process [BFO:0000050 relation] BFO:0000050  heart process (GO:0003015)
Children of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process (GO:0086096)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process (GO:0140195) [RO:0002213 relation] RO:0002213  adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process
negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process (GO:0140194) [RO:0002212 relation] RO:0002212  adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process
regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process (GO:0140193) [RO:0002211 relation] RO:0002211  adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process
None.