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Term Information

Accession
GO:0071754
Name
IgM immunoglobulin complex, circulating
Ontology
cellular_component
Synonyms
IgM antibody
Alternate IDs
None
Definition
A polymer of five or six IgM core units each composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds; the individual IgM core units are held together via disulfide bonds with a single J chain polypeptide acting as a bridge between two of the polymeric units. Circulating IgM is present in the extracellular space, in mucosal areas or other tissues, or in the blood or lymph. Source: ISBN:0781765196, GOC:add, PMID:20176268
Comment
Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
History
See term history for GO:0071754 at QuickGO
Subset
None
Feedback
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Graph of GO:0071754

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Parents of IgM immunoglobulin complex, circulating (GO:0071754)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
IgM immunoglobulin complex, circulating [is_a relation] is_a  immunoglobulin complex, circulating (GO:0042571)
IgM immunoglobulin complex, circulating [is_a relation] is_a  IgM immunoglobulin complex (GO:0071753)
Children of IgM immunoglobulin complex, circulating (GO:0071754)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
pentameric IgM immunoglobulin complex (GO:0071756) [is_a relation] is_a  IgM immunoglobulin complex, circulating
hexameric IgM immunoglobulin complex (GO:0071757) [is_a relation] is_a  IgM immunoglobulin complex, circulating
None.