Planteome: Term Details for "polymeric IgA immunoglobulin complex" (GO:0071749)

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Term Information

Accession: GO:0071749
Name: polymeric IgA immunoglobulin complex
Ontology: cellular_component
Synonyms: pIgA antibody, polymeric IgA antibody, pIgA1 antibody, polymeric IgA1 antibody
Alternate IDs: None
Definition: A protein complex composed of two, three, or four monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through disulfide binded monomers of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. Source: ISBN:0781765196, PMID:16362985, GOC:add
Comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Dimeric IgA is by far the most common form of polymeric IgA. In human only the IgA1 isotype is capable of a polymeric forms.
History: See term history for GO:0071749 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to polymeric IgA immunoglobulin complex.; Link to all direct and indirect annotations to polymeric IgA immunoglobulin complex.; Link to all direct and indirect annotations download (limited to first 10,000) for polymeric IgA immunoglobulin complex.
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GO:0110165 cellular anatomical entity
GO:0005575 cellular_component
GO:0005576 extracellular region
GO:0032991 protein-containing complex
GO:0005615 extracellular space
GO:0019814 immunoglobulin complex
GO:0071745 IgA immunoglobulin complex
GO:0042571 immunoglobulin complex, circulating
GO:0071746 IgA immunoglobulin complex, circulating
GO:0071749 polymeric IgA immunoglobulin complex
GO:0071750 dimeric IgA immunoglobulin complex
GO:0071751 secretory IgA immunoglobulin complex

Parents of polymeric IgA immunoglobulin complex (GO:0071749)

subject	relation	object
polymeric IgA immunoglobulin complex	is_a	IgA immunoglobulin complex, circulating (GO:0071746)

Children of polymeric IgA immunoglobulin complex (GO:0071749)

subject	relation	object
secretory IgA immunoglobulin complex (GO:0071751)	is_a	polymeric IgA immunoglobulin complex
dimeric IgA immunoglobulin complex (GO:0071750)	is_a	polymeric IgA immunoglobulin complex