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Term Information

Accession
GO:0071712
Name
ER-associated misfolded protein catabolic process
Ontology
biological_process
Synonyms
ER-associated misfolded protein breakdown, ER-associated misfolded protein catabolism, ER-associated misfolded protein degradation, endoplasmic reticulum-associated misfolded protein catabolic process, endoplasmic reticulum-associated misfolded protein catabolism, proteasomal protein catabolism of misfolded ER proteins
Alternate IDs
None
Definition
The chemical reactions and pathways resulting in the breakdown of misfolded proteins transported from the endoplasmic reticulum and targeted to cytoplasmic proteasomes for degradation. Source: PMID:14607247, GOC:vw, PMID:19520858, GOC:mah
Comment
See also the biological process terms 'unfolded protein response ; GO:0030968' and 'retrograde protein transport, ER to cytosol ; GO:0030970'.
History
See term history for GO:0071712 at QuickGO
Subset
None
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Graph of GO:0071712

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Parents of ER-associated misfolded protein catabolic process (GO:0071712)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ER-associated misfolded protein catabolic process [BFO:0000050 relation] BFO:0000050  cellular response to misfolded protein (GO:0071218)
ER-associated misfolded protein catabolic process [is_a relation] is_a  protein quality control for misfolded or incompletely synthesized proteins (GO:0006515)
ER-associated misfolded protein catabolic process [is_a relation] is_a  ERAD pathway (GO:0036503)

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