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Term Information

Accession
GO:0071159
Name
NF-kappaB complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A protein complex that consists of a homo- or heterodimer of members of a family of structurally related proteins that contain a conserved N-terminal region called the Rel homology domain (RHD). In the nucleus, NF-kappaB complexes act as transcription factors. In unstimulated cells, NF-kappaB dimers are sequestered in the cytoplasm by IkappaB monomers; signals that induce NF-kappaB activity cause degradation of IkappaB, allowing NF-kappaB dimers to translocate to the nucleus and induce gene expression. Source: ISBN:0849327946
Comment
None
History
See term history for GO:0071159 at QuickGO
Subset
None
Feedback
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Graph of GO:0071159

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Parents of NF-kappaB complex (GO:0071159)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
NF-kappaB complex [is_a relation] is_a  protein-containing complex (GO:0032991)
NF-kappaB complex [BFO:0000050 relation] BFO:0000050  intracellular anatomical structure (GO:0005622)
Children of NF-kappaB complex (GO:0071159)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
NF-kappaB p50/p65 complex (GO:0035525) [is_a relation] is_a  NF-kappaB complex
None.