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Term Information

Accession
GO:0070976
Name
TIR domain binding
Ontology
molecular_function
Synonyms
Toll-Interleukin receptor domain binding
Alternate IDs
None
Definition
Binding to a Toll-Interleukin receptor (TIR) domain of a protein. The TIR domain is an intracellular 200 residue domain that is found in the Toll protein, the interleukin-1 receptor (IL-1R), and MyD88; it contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. Source: GOC:mah, InterPro:IPR000157
Comment
None
History
See term history for GO:0070976 at QuickGO
Subset
goslim_chembl
Feedback
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Parents of TIR domain binding (GO:0070976)
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TIR domain binding [is_a relation] is_a  protein domain specific binding (GO:0019904)

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