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Term Information

Accession
GO:0070745
Name
interleukin-35 complex
Ontology
cellular_component
Synonyms
IL-35 complex, EBI3, IL12A, p35
Alternate IDs
None
Definition
A protein complex that is composed of an interleukin-12 alpha subunit (p35, product of the IL12A gene) and an EBI3 subunit and is secreted into the extracellular space. Source: GOC:add, PMID:19161429, PMID:19161428
Comment
Note that this heterodimeric cytokine utilizes the same IL-12p35 subunit as its alpha chain as IL-12 uses and the same EBI3 subunit (product of EBI3, Epstein-Barr virus induced gene 3) as its beta chain as IL-27 uses. IL-35 requires both subunits -- there is no separate IL35 gene.
History
See term history for GO:0070745 at QuickGO
Subset
None
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Graph of GO:0070745

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Parents of interleukin-35 complex (GO:0070745)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
interleukin-35 complex [is_a relation] is_a  protein-containing complex (GO:0032991)
interleukin-35 complex [BFO:0000050 relation] BFO:0000050  extracellular space (GO:0005615)

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