Planteome: Term Details for "base J metabolic process" (GO:0070580)

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Term Information

Accession: GO:0070580
Name: base J metabolic process
Ontology: biological_process
Synonyms: base J metabolism, beta-D-glucosyl-HOMedU metabolic process, beta-D-glucosyl-hydroxymethyluracil metabolism
Alternate IDs: None
Definition: The chemical reactions and pathways involving base J (beta-D-glucosyl-hydroxymethyluracil), a hypermodified thymidine residue found in the genome of kinetoplastid parasites. This modified base is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. The base is synthesized in a two-step pathway. Initially, a thymidine residue in DNA is hydroxylated by a thymidine hydroxylase (TH) to form the intermediate hydroxymethyluracil, which is then glucosylated to form base J. Source: PMID:19114062
Comment: None
History: See term history for GO:0070580 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to base J metabolic process.; Link to all direct and indirect annotations to base J metabolic process.; Link to all direct and indirect annotations download (limited to first 10,000) for base J metabolic process.
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