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Term Information

Accession
GO:0070549
Name
siRNA-mediated gene silencing by inhibition of translation
Ontology
biological_process
Synonyms
RNA interference, negative regulation of translation, down regulation of translation involved in RNA interference, down-regulation of translation involved in RNA interference, downregulation of translation involved in RNA interference, inhibition of translation involved in RNA interference, negative regulation of translation involved in RNA interference
Alternate IDs
None
Definition
An siRNA-mediated post-transcriptional gene silencing pathway that blocks the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), an siRNA will typically mediate repression of translation if the siRNA perfectly complements elements located in the 3' untranslated region of target mRNAs. Source: GOC:mah, PMID:18771919
Comment
None
History
See term history for GO:0070549 at QuickGO
Subset
None
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Graph of GO:0070549

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Parents of siRNA-mediated gene silencing by inhibition of translation (GO:0070549)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
siRNA-mediated gene silencing by inhibition of translation [is_a relation] is_a  siRNA-mediated gene silencing (GO:0140766)
siRNA-mediated gene silencing by inhibition of translation [is_a relation] is_a  negative regulation of translation (GO:0017148)

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