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death domain binding
Term Information
Accession
GO:0070513
Name
death domain binding
Ontology
molecular_function
Synonyms
None
Alternate IDs
None
Definition
Binding to a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB.
Source:
GOC:BHF,
Pfam:PF00531,
InterPro:IPR000488,
GOC:rl
Comment
For binding to the death effector domain, consider instead the term 'death effector domain binding ; GO:0035877'.
Link
to all annotated objects annotated to death domain binding.
Link
to all direct and indirect annotations
to death domain binding.
Link
to all direct and indirect annotations download (limited to first 10,000)
for death domain binding.
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