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Term Information

Accession
GO:0070513
Name
death domain binding
Ontology
molecular_function
Synonyms
None
Alternate IDs
None
Definition
Binding to a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB. Source: GOC:BHF, Pfam:PF00531, InterPro:IPR000488, GOC:rl
Comment
For binding to the death effector domain, consider instead the term 'death effector domain binding ; GO:0035877'.
History
See term history for GO:0070513 at QuickGO
Subset
None
Feedback
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Graph of GO:0070513

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Parents of death domain binding (GO:0070513)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
death domain binding [is_a relation] is_a  protein domain specific binding (GO:0019904)
Children of death domain binding (GO:0070513)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
BH3 domain binding (GO:0051434) [is_a relation] is_a  death domain binding
None.