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tyrosyl-DNA phosphodiesterase activity

Term Information

Accession
GO:0070259
Name
tyrosyl-DNA phosphodiesterase activity
Ontology
molecular_function
Synonyms
None
Alternate IDs
None
Definition
Catalysis of the hydrolysis of phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between a DNA topoisomerase and DNA. Source: GOC:elh, PMID:16751265
Comment
See also the molecular function term 'DNA topoisomerase type I activity ; GO:0003917'.
History
See term history for GO:0070259 at QuickGO
Subset
None
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Graph of GO:0070259

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Parents of tyrosyl-DNA phosphodiesterase activity (GO:0070259)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
tyrosyl-DNA phosphodiesterase activity [is_a relation] is_a  phosphoric diester hydrolase activity (GO:0008081)
tyrosyl-DNA phosphodiesterase activity [is_a relation] is_a  catalytic activity, acting on DNA (GO:0140097)
Children of tyrosyl-DNA phosphodiesterase activity (GO:0070259)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
5'-tyrosyl-DNA phosphodiesterase activity (GO:0070260) [is_a relation] is_a  tyrosyl-DNA phosphodiesterase activity
3'-tyrosyl-DNA phosphodiesterase activity (GO:0017005) [is_a relation] is_a  tyrosyl-DNA phosphodiesterase activity
None.