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Term Information

Accession
GO:0060856
Name
establishment of blood-brain barrier
Ontology
biological_process
Synonyms
establishment of BBB, establishment of blood/brain barrier
Alternate IDs
None
Definition
Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier. Source: GOC:dph, PMID:20080302, GOC:sart, GOC:aruk, PMID:30280653
Comment
None
History
See term history for GO:0060856 at QuickGO
Subset
None
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Graph of GO:0060856

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Parents of establishment of blood-brain barrier (GO:0060856)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
establishment of blood-brain barrier [is_a relation] is_a  cell development (GO:0048468)
establishment of blood-brain barrier [BFO:0000050 relation] BFO:0000050  central nervous system development (GO:0007417)
Children of establishment of blood-brain barrier (GO:0060856)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
establishment of endothelial blood-brain barrier (GO:0014045) [is_a relation] is_a  establishment of blood-brain barrier
positive regulation of establishment of blood-brain barrier (GO:0090211) [RO:0002213 relation] RO:0002213  establishment of blood-brain barrier
negative regulation of establishment of blood-brain barrier (GO:0090212) [RO:0002212 relation] RO:0002212  establishment of blood-brain barrier
regulation of establishment of blood-brain barrier (GO:0090210) [RO:0002211 relation] RO:0002211  establishment of blood-brain barrier
establishment of glial blood-brain barrier (GO:0060857) [is_a relation] is_a  establishment of blood-brain barrier
None.