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Term Information

Accession
GO:0051920
Name
peroxiredoxin activity
Ontology
molecular_function
Synonyms
PRDX activity, Prx activity, thiol-containing-reductant:hydroperoxide oxidoreductase activity, AhpC activity, alkyl hydroperoxide reductase C22 activity
Alternate IDs
None
Definition
Catalysis of the reaction: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH. Source: RHEA:10008, EC:1.11.1.15
Comment
Includes redox chemistry as part of the catalytic reaction (2 R'-SH = R'-S-S-R'), where R' refers to peroxiredoxin itself). Not to be confused with GO:0004601 (peroxidase activity, EC:1.11.1.7), which has a different reaction mechanism.
History
See term history for GO:0051920 at QuickGO
Subset
None
Feedback
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Graph of GO:0051920

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Parents of peroxiredoxin activity (GO:0051920)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
peroxiredoxin activity [is_a relation] is_a  antioxidant activity (GO:0016209)
peroxiredoxin activity [is_a relation] is_a  oxidoreductase activity, acting on peroxide as acceptor (GO:0016684)
Children of peroxiredoxin activity (GO:0051920)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
tryparedoxin peroxidase activity (GO:0033196) [is_a relation] is_a  peroxiredoxin activity
thioredoxin peroxidase activity (GO:0008379) [is_a relation] is_a  peroxiredoxin activity
peroxynitrite reductase activity (GO:0072541) [is_a relation] is_a  peroxiredoxin activity