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Term Information

Accession
GO:0048289
Name
isotype switching to IgE isotypes
Ontology
biological_process
Synonyms
class switch recombination to IgE isotypes, class switching to IgE isotypes, isotype switch recombination to IgE isotypes
Alternate IDs
None
Definition
The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus. Source: PMID:2113175, PMID:9186655, ISBN:0781735149, PMID:12370374
Comment
None
History
See term history for GO:0048289 at QuickGO
Subset
None
Feedback
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Graph of GO:0048289

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Parents of isotype switching to IgE isotypes (GO:0048289)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
isotype switching to IgE isotypes [is_a relation] is_a  isotype switching (GO:0045190)
Children of isotype switching to IgE isotypes (GO:0048289)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of isotype switching to IgE isotypes (GO:0048295) [RO:0002213 relation] RO:0002213  isotype switching to IgE isotypes
regulation of isotype switching to IgE isotypes (GO:0048293) [RO:0002211 relation] RO:0002211  isotype switching to IgE isotypes
interleukin-4-dependent isotype switching to IgE isotypes (GO:0035708) [is_a relation] is_a  isotype switching to IgE isotypes
negative regulation of isotype switching to IgE isotypes (GO:0048294) [RO:0002212 relation] RO:0002212  isotype switching to IgE isotypes
None.