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Term Information

Accession
GO:0045841
Name
negative regulation of mitotic metaphase/anaphase transition
Ontology
biological_process
Synonyms
down regulation of mitotic metaphase/anaphase transition, down-regulation of mitotic metaphase/anaphase transition, downregulation of mitotic metaphase/anaphase transition, inhibition of mitotic metaphase/anaphase transition
Alternate IDs
None
Definition
Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin. Source: GOC:go_curators
Comment
None
History
See term history for GO:0045841 at QuickGO
Subset
None
Feedback
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Graph of GO:0045841

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Parents of negative regulation of mitotic metaphase/anaphase transition (GO:0045841)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of mitotic metaphase/anaphase transition [is_a relation] is_a  negative regulation of mitotic nuclear division (GO:0045839)
negative regulation of mitotic metaphase/anaphase transition [RO:0002212 relation] RO:0002212  metaphase/anaphase transition of mitotic cell cycle (GO:0007091)
negative regulation of mitotic metaphase/anaphase transition [is_a relation] is_a  regulation of mitotic metaphase/anaphase transition (GO:0030071)
negative regulation of mitotic metaphase/anaphase transition [is_a relation] is_a  negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)
negative regulation of mitotic metaphase/anaphase transition [is_a relation] is_a  negative regulation of mitotic sister chromatid separation (GO:2000816)
negative regulation of mitotic metaphase/anaphase transition [is_a relation] is_a  negative regulation of mitotic cell cycle phase transition (GO:1901991)
Children of negative regulation of mitotic metaphase/anaphase transition (GO:0045841)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
mitotic spindle assembly checkpoint (GO:0007094) [is_a relation] is_a  negative regulation of mitotic metaphase/anaphase transition
None.