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Term Information

Accession
GO:0045829
Name
negative regulation of isotype switching
Ontology
biological_process
Synonyms
down regulation of isotype switching, down-regulation of isotype switching, downregulation of isotype switching, negative regulation of class switch recombination, negative regulation of class switching, negative regulation of isotype switch recombination, inhibition of isotype switching
Alternate IDs
None
Definition
Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching. Source: GOC:go_curators
Comment
None
History
See term history for GO:0045829 at QuickGO
Subset
None
Feedback
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Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Graph of GO:0045829

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Parents of negative regulation of isotype switching (GO:0045829)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of isotype switching [is_a relation] is_a  negative regulation of B cell activation (GO:0050869)
negative regulation of isotype switching [is_a relation] is_a  negative regulation of DNA recombination (GO:0045910)
negative regulation of isotype switching [RO:0002212 relation] RO:0002212  isotype switching (GO:0045190)
negative regulation of isotype switching [is_a relation] is_a  negative regulation of immunoglobulin mediated immune response (GO:0002890)
negative regulation of isotype switching [is_a relation] is_a  regulation of isotype switching (GO:0045191)
negative regulation of isotype switching [is_a relation] is_a  negative regulation of immunoglobulin production (GO:0002638)
negative regulation of isotype switching [is_a relation] is_a  negative regulation of multicellular organismal process (GO:0051241)
negative regulation of isotype switching [is_a relation] is_a  negative regulation of developmental process (GO:0051093)
Children of negative regulation of isotype switching (GO:0045829)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of isotype switching to IgE isotypes (GO:0048294) [is_a relation] is_a  negative regulation of isotype switching
negative regulation of isotype switching to IgA isotypes (GO:0048297) [is_a relation] is_a  negative regulation of isotype switching
negative regulation of isotype switching to IgG isotypes (GO:0048303) [is_a relation] is_a  negative regulation of isotype switching
negative regulation of isotype switching to IgD isotypes (GO:0048300) [is_a relation] is_a  negative regulation of isotype switching
None.