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Term Information

Accession
GO:0045254
Name
pyruvate dehydrogenase complex
Ontology
cellular_component
Synonyms
pyruvate dehydrogenase complex (lipoamide), dihydrolipoyl dehydrogenase complex
Alternate IDs
GO:0009364
Definition
Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Source: ISBN:0716720094
Comment
Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The functions of this complex are represented by the molecular function terms 'pyruvate dehydrogenase (lipoamide) activity ; GO:0004739', 'dihydrolipoamide S-acetyltransferase activity ; GO:0004742', and 'dihydrolipoamide dehydrogenase activity ; GO:0004148'.
History
See term history for GO:0045254 at QuickGO
Subset
goslim_pir
Feedback
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Graph of GO:0045254

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Parents of pyruvate dehydrogenase complex (GO:0045254)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
pyruvate dehydrogenase complex [is_a relation] is_a  oxidoreductase complex (GO:1990204)
pyruvate dehydrogenase complex [BFO:0000050 relation] BFO:0000050  cytoplasm (GO:0005737)
Children of pyruvate dehydrogenase complex (GO:0045254)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
mitochondrial pyruvate dehydrogenase complex (GO:0005967) [is_a relation] is_a  pyruvate dehydrogenase complex
cytosolic pyruvate dehydrogenase complex (GO:0045250) [is_a relation] is_a  pyruvate dehydrogenase complex
plastid pyruvate dehydrogenase complex (GO:0010240) [is_a relation] is_a  pyruvate dehydrogenase complex