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synapse

Term Information

Accession
GO:0045202
Name
synapse
Ontology
cellular_component
Synonyms
synaptic junction, electrotonic synapse, mixed synapse
Alternate IDs
None
Definition
The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. Source: ISBN:0198506732, PMID:29383328, PMID:24619342, GOC:aruk, PMID:31998110
Comment
None
History
See term history for GO:0045202 at QuickGO
Subset
goslim_flybase_ribbon
goslim_drosophila
goslim_mouse
goslim_agr
goslim_synapse
goslim_pir
Feedback
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Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Graph of GO:0045202

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Parents of synapse (GO:0045202)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
synapse [is_a relation] is_a  cell junction (GO:0030054)
Children of synapse (GO:0045202)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
presynapse (GO:0098793) [BFO:0000050 relation] BFO:0000050  synapse
neuron to neuron synapse (GO:0098984) [is_a relation] is_a  synapse
dopaminergic synapse (GO:0098691) [is_a relation] is_a  synapse
neuromuscular junction (GO:0031594) [is_a relation] is_a  synapse
excitatory synapse (GO:0060076) [is_a relation] is_a  synapse
protein catabolic process at synapse (GO:0140246) [BFO:0000066 relation] BFO:0000066  synapse
polyadic synapse (GO:0098979) [is_a relation] is_a  synapse
regulation of translation at synapse (GO:0140243) [BFO:0000066 relation] BFO:0000066  synapse
Schaffer collateral - CA1 synapse (GO:0098685) [is_a relation] is_a  synapse
perforant pathway to dendrate granule cell synapse (GO:0140240) [is_a relation] is_a  synapse
signal release from synapse (GO:0099643) [BFO:0000066 relation] BFO:0000066  synapse
cholinergic synapse (GO:0098981) [is_a relation] is_a  synapse
glutamatergic synapse (GO:0098978) [is_a relation] is_a  synapse
ribbon synapse (GO:0097470) [is_a relation] is_a  synapse
regulation protein catabolic process at synapse (GO:0140250) [BFO:0000066 relation] BFO:0000066  synapse
inhibitory synapse (GO:0060077) [is_a relation] is_a  synapse
synaptic membrane (GO:0097060) [BFO:0000050 relation] BFO:0000050  synapse
noradrenergic synapse (GO:0098692) [is_a relation] is_a  synapse
serotonergic synapse (GO:0099154) [is_a relation] is_a  synapse
vesicle-mediated transport in synapse (GO:0099003) [BFO:0000066 relation] BFO:0000066  synapse
glycinergic synapse (GO:0098690) [is_a relation] is_a  synapse
translation at synapse (GO:0140241) [BFO:0000066 relation] BFO:0000066  synapse
cerebellar Golgi cell to granule cell synapse (GO:0099192) [is_a relation] is_a  synapse
postsynapse (GO:0098794) [BFO:0000050 relation] BFO:0000050  synapse
GABA-ergic synapse (GO:0098982) [is_a relation] is_a  synapse
synaptic signaling (GO:0099536) [BFO:0000066 relation] BFO:0000066  synapse
structural constituent of synapse (GO:0098918) [BFO:0000066 relation] BFO:0000066  synapse
NIF_Subcellular
sao914572699
Wikipedia
Chemical_synapse