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Term Information

Accession
GO:0045107
Name
intermediate filament polymerization
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
Assembly of intermediate filaments by the addition of component monomers to a filament. Polymerization of intermediate filament proteins results from interactions among several distinct binding sites on the constituent proteins. Nuclear lamin head-to-tail polymers arise from one such interaction. Deletion analysis localized the binding sites to the ends of the rod domain that are highly conserved among all intermediate filament proteins. Data indicate that one type of interaction in intermediate filament protein polymerization is the longitudinal binding of dimers via the conserved end segments of the coiled-coil rod domain. Source: GOC:mah, PMID:8776884
Comment
None
History
See term history for GO:0045107 at QuickGO
Subset
None
Feedback
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Graph of GO:0045107

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Parents of intermediate filament polymerization (GO:0045107)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
intermediate filament polymerization [is_a relation] is_a  intermediate filament polymerization or depolymerization (GO:0045105)
intermediate filament polymerization [is_a relation] is_a  protein polymerization (GO:0051258)
Children of intermediate filament polymerization (GO:0045107)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of intermediate filament polymerization (GO:0030839) [RO:0002211 relation] RO:0002211  intermediate filament polymerization
positive regulation of intermediate filament polymerization (GO:0030841) [RO:0002213 relation] RO:0002213  intermediate filament polymerization
negative regulation of intermediate filament polymerization (GO:0030840) [RO:0002212 relation] RO:0002212  intermediate filament polymerization
None.