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Term Information

Accession
GO:0045047
Name
protein targeting to ER
Ontology
biological_process
Synonyms
protein targeting to endoplasmic reticulum, protein-ER targeting, protein-endoplasmic reticulum targeting
Alternate IDs
None
Definition
The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane. Source: ISBN:0716731363
Comment
None
History
See term history for GO:0045047 at QuickGO
Subset
None
Feedback
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Graph of GO:0045047

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Parents of protein targeting to ER (GO:0045047)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
protein targeting to ER [is_a relation] is_a  protein targeting (GO:0006605)
protein targeting to ER [is_a relation] is_a  establishment of protein localization to endoplasmic reticulum (GO:0072599)
Children of protein targeting to ER (GO:0045047)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
posttranslational protein targeting to endoplasmic reticulum membrane (GO:0006620) [is_a relation] is_a  protein targeting to ER
SRP-dependent cotranslational protein targeting to membrane (GO:0006614) [is_a relation] is_a  protein targeting to ER
None.