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Term Information

Accession
GO:0045003
Name
double-strand break repair via synthesis-dependent strand annealing
Ontology
biological_process
Synonyms
mitotic gene conversion, SDSA
Alternate IDs
None
Definition
SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break. Source: PMID:10357855
Comment
None
History
See term history for GO:0045003 at QuickGO
Subset
None
Feedback
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Graph of GO:0045003

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Parents of double-strand break repair via synthesis-dependent strand annealing (GO:0045003)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
double-strand break repair via synthesis-dependent strand annealing [is_a relation] is_a  double-strand break repair via homologous recombination (GO:0000724)
Children of double-strand break repair via synthesis-dependent strand annealing (GO:0045003)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
DNA double-strand break processing involved in repair via synthesis-dependent strand annealing (GO:0010791) [BFO:0000050 relation] BFO:0000050  double-strand break repair via synthesis-dependent strand annealing
DNA recombinase assembly (GO:0000730) [BFO:0000050 relation] BFO:0000050  double-strand break repair via synthesis-dependent strand annealing
meiotic strand displacement involved in double-strand break repair via SDSA (GO:1902346) [BFO:0000050 relation] BFO:0000050  double-strand break repair via synthesis-dependent strand annealing
heteroduplex formation involved in double-strand break repair via synthesis-dependent strand annealing (GO:0010709) [BFO:0000050 relation] BFO:0000050  double-strand break repair via synthesis-dependent strand annealing
None.