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Term Information

Accession
GO:0044612
Name
nuclear pore linkers
Ontology
cellular_component
Synonyms
Nic96 complex, Nup82 complex
Alternate IDs
None
Definition
A substructure of the nuclear pore complex (NPC) that serves to connect members of the central transport channel (composed of FG-nucleoporins) to the core scaffold (composed of the inner and outer NPC rings). In S. cerevisiae, the linkers are Nic96p and Nup82p. In vertebrates, they are Nup93 and Nup88. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. Both linkers can be isolated in association with specific FG-nucleoporins, complexes that are sometimes referred to as the Nic96 complex (Nic96p-Nsp1p-Nup49p-Nup57p) and the Nup82 complex (Nup82p-Nup116p-Nup159p-Gle2p). Source: PMID:18046406, GOC:dgf, PMID:19524430, PMID:20947011, PMID:22419078
Comment
None
History
See term history for GO:0044612 at QuickGO
Subset
None
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Graph of GO:0044612

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Parents of nuclear pore linkers (GO:0044612)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nuclear pore linkers [is_a relation] is_a  protein-containing complex (GO:0032991)
nuclear pore linkers [BFO:0000050 relation] BFO:0000050  nuclear pore (GO:0005643)

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