Planteome: Term Details for "PCNA complex" (GO:0043626)

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Term Information

Accession: GO:0043626
Name: PCNA complex
Ontology: cellular_component
Synonyms: PCNA homotrimer, proliferating cell nuclear antigen complex, sliding clamp
Alternate IDs: None
Definition: A protein complex composed of three identical PCNA monomers, each comprising two similar domains, which are joined in a head-to-tail arrangement to form a homotrimer. Forms a ring-like structure in solution, with a central hole sufficiently large to accommodate the double helix of DNA. Originally characterized as a DNA sliding clamp for replicative DNA polymerases and as an essential component of the replisome, and has also been shown to be involved in other processes including Okazaki fragment processing, DNA repair, translesion DNA synthesis, DNA methylation, chromatin remodeling and cell cycle regulation. Source: PMID:12829735, GOC:jl
Comment: None
History: See term history for GO:0043626 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to PCNA complex.; Link to all direct and indirect annotations to PCNA complex.; Link to all direct and indirect annotations download (limited to first 10,000) for PCNA complex.
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