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Term Information

Accession
GO:0043540
Name
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex
Ontology
cellular_component
Synonyms
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 complex, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 complex, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 complex, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 complex
Alternate IDs
None
Definition
A homodimeric, bifunctional enzyme complex which catalyzes the synthesis and degradation of fructose 2,6-bisphosphate, and is required for both glycolysis and gluconeogenesis. Source: GOC:so, GOC:jl
Comment
Note that we use this single class to represent all 4 isoforms of this complex. We decided to do this because the isoforms do not differ in function, rather in expression and regulation. We may want to revisit this in future.
History
See term history for GO:0043540 at QuickGO
Subset
None
Feedback
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Graph of GO:0043540

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Parents of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex (GO:0043540)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [is_a relation] is_a  transferase complex, transferring phosphorus-containing groups (GO:0061695)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [BFO:0000050 relation] BFO:0000050  cytosol (GO:0005829)

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