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Fanconi anaemia nuclear complex
Term Information
Accession
GO:0043240
Name
Fanconi anaemia nuclear complex
Ontology
cellular_component
Synonyms
FA complex, FA core complex, FA nuclear complex, Fanconi anaemia complex
Alternate IDs
None
Definition
A protein complex composed of the Fanconi anaemia (FA) proteins including A, C, E, G and F (FANCA-F). Functions in the activation of the downstream protein FANCD2 by monoubiquitylation, and is essential for protection against chromosome breakage.
Source:PMID:12093742,
GOC:jl
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