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Term Information

Accession
GO:0043161
Name
proteasome-mediated ubiquitin-dependent protein catabolic process
Ontology
biological_process
Synonyms
proteasomal pathway, proteasomal ubiquitin-dependent protein breakdown, proteasomal ubiquitin-dependent protein catabolic process, proteasomal ubiquitin-dependent protein catabolism, proteasomal ubiquitin-dependent protein degradation, proteasomal processing, proteasome pathway
Alternate IDs
None
Definition
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. Source: GOC:go_curators
Comment
None
History
See term history for GO:0043161 at QuickGO
Subset
None
Feedback
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Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Graph of GO:0043161

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Parents of proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
proteasome-mediated ubiquitin-dependent protein catabolic process [is_a relation] is_a  ubiquitin-dependent protein catabolic process (GO:0006511)
proteasome-mediated ubiquitin-dependent protein catabolic process [is_a relation] is_a  proteasomal protein catabolic process (GO:0010498)
Children of proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nuclear protein quality control by the ubiquitin-proteasome system (GO:0071630) [is_a relation] is_a  proteasome-mediated ubiquitin-dependent protein catabolic process
anaphase-promoting complex-dependent catabolic process (GO:0031145) [is_a relation] is_a  proteasome-mediated ubiquitin-dependent protein catabolic process
ubiquitin-dependent protein catabolic process via the C-end degron rule pathway (GO:0140627) [is_a relation] is_a  proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of transcription by transcription factor catabolism (GO:0010620) [is_a relation] is_a  proteasome-mediated ubiquitin-dependent protein catabolic process
ribosome-associated ubiquitin-dependent protein catabolic process (GO:1990116) [is_a relation] is_a  proteasome-mediated ubiquitin-dependent protein catabolic process
ubiquitin-dependent protein catabolic process via the N-end rule pathway (GO:0071596) [is_a relation] is_a  proteasome-mediated ubiquitin-dependent protein catabolic process
cytoplasm protein quality control by the ubiquitin-proteasome system (GO:0071629) [is_a relation] is_a  proteasome-mediated ubiquitin-dependent protein catabolic process
mitochondria-associated ubiquitin-dependent protein catabolic process (GO:0072671) [is_a relation] is_a  proteasome-mediated ubiquitin-dependent protein catabolic process
ubiquitin-dependent ERAD pathway (GO:0030433) [is_a relation] is_a  proteasome-mediated ubiquitin-dependent protein catabolic process
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031146) [is_a relation] is_a  proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032436) [RO:0002213 relation] RO:0002213  proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032435) [RO:0002212 relation] RO:0002212  proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032434) [RO:0002211 relation] RO:0002211  proteasome-mediated ubiquitin-dependent protein catabolic process
stress-induced homeostatically regulated protein degradation pathway (GO:0120174) [is_a relation] is_a  proteasome-mediated ubiquitin-dependent protein catabolic process
None.