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Term Information

Accession
GO:0042288
Name
MHC class I protein binding
Ontology
molecular_function
Synonyms
major histocompatibility complex class I binding, T cell receptor activity, alpha-beta T cell receptor activity, gamma-delta T cell receptor activity, major histocompatibility complex class I ligand
Alternate IDs
None
Definition
Binding to a major histocompatibility complex class I molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation. Source: GOC:jl
Comment
Note that this term does not include binding to the antigen peptide bound to the MHC protein. Consider also annotating to the molecular function term 'peptide antigen binding ; GO:0042605' or one of its children.
History
See term history for GO:0042288 at QuickGO
Subset
None
Feedback
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Graph of GO:0042288

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Parents of MHC class I protein binding (GO:0042288)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
MHC class I protein binding [is_a relation] is_a  MHC protein binding (GO:0042287)
Children of MHC class I protein binding (GO:0042288)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
MHC class I receptor activity (GO:0032393) [BFO:0000051 relation] BFO:0000051  MHC class I protein binding
MHC class I protein binding, via lateral surface (GO:0023028) [is_a relation] is_a  MHC class I protein binding
MHC class I protein binding, via antigen binding groove (GO:0023027) [is_a relation] is_a  MHC class I protein binding
None.