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Term Information

Accession
GO:0038179
Name
neurotrophin signaling pathway
Ontology
biological_process
Synonyms
neurotrophin receptor signaling pathway
Alternate IDs
None
Definition
A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Neurotrophins are a family of secreted growth factors that induce the survival, development, and function of neurons. Source: GOC:signaling, GOC:bf, Wikipedia:Neurotrophin, GOC:jc, PMID:17466268
Comment
There are two classes of receptors for neurotrophins: p75 and the Trk family of tyrosine kinase receptors.
History
See term history for GO:0038179 at QuickGO
Subset
None
Feedback
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Graph of GO:0038179

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Parents of neurotrophin signaling pathway (GO:0038179)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
neurotrophin signaling pathway [BFO:0000050 relation] BFO:0000050  cellular response to growth factor stimulus (GO:0071363)
neurotrophin signaling pathway [is_a relation] is_a  cell surface receptor signaling pathway (GO:0007166)
Children of neurotrophin signaling pathway (GO:0038179)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nerve growth factor signaling pathway (GO:0038180) [is_a relation] is_a  neurotrophin signaling pathway
neurotrophin TRK receptor signaling pathway (GO:0048011) [is_a relation] is_a  neurotrophin signaling pathway
neurotrophin receptor activity (GO:0005030) [BFO:0000050 relation] BFO:0000050  neurotrophin signaling pathway
None.