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Term Information

Accession
GO:0038129
Name
ERBB3 signaling pathway
Ontology
biological_process
Synonyms
ERBB3 signalling pathway, HER3 signaling pathway, receptor tyrosine-protein kinase erbB-3 signaling pathway
Alternate IDs
None
Definition
A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB3 on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB3 receptors have impaired kinase activity and rely on the kinase activity of the heterodimer partner for activation and signal transmission. Source: Reactome:R-HSA-1247497, PMID:16460914, GOC:jc
Comment
None
History
See term history for GO:0038129 at QuickGO
Subset
None
Feedback
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Graph of GO:0038129

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Parents of ERBB3 signaling pathway (GO:0038129)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ERBB3 signaling pathway [is_a relation] is_a  ERBB signaling pathway (GO:0038127)
Children of ERBB3 signaling pathway (GO:0038129)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ERBB3-ERBB4 signaling pathway (GO:0038136) [is_a relation] is_a  ERBB3 signaling pathway
negative regulation of ERBB3 signaling pathway (GO:1905579) [RO:0002212 relation] RO:0002212  ERBB3 signaling pathway
positive regulation of ERBB3 signaling pathway (GO:1905580) [RO:0002213 relation] RO:0002213  ERBB3 signaling pathway
regulation of ERBB3 signaling pathway (GO:1905578) [RO:0002211 relation] RO:0002211  ERBB3 signaling pathway
ERBB2-ERBB3 signaling pathway (GO:0038133) [is_a relation] is_a  ERBB3 signaling pathway
None.