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Term Information

Accession
GO:0038011
Name
negative regulation of signal transduction by receptor internalization
Ontology
biological_process
Synonyms
negative regulation of signaling pathway by receptor endocytosis
Alternate IDs
None
Definition
Any process in which internalization of a signaling receptor stops, prevents, or reduces the frequency, rate or extent of signal transduction. Receptor internalization can attenuate or reduce the strength of signaling by reducing the concentration of cell surface receptors available to ligands. Source: GOC:signaling, PMID:19696798, GOC:bf, PMID:17908284
Comment
None
History
See term history for GO:0038011 at QuickGO
Subset
None
Feedback
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Graph of GO:0038011

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Parents of negative regulation of signal transduction by receptor internalization (GO:0038011)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of signal transduction by receptor internalization [is_a relation] is_a  regulation of signal transduction by receptor internalization (GO:0038009)
negative regulation of signal transduction by receptor internalization [RO:0002212 relation] RO:0002212  signal transduction (GO:0007165)
negative regulation of signal transduction by receptor internalization [is_a relation] is_a  negative regulation of signal transduction (GO:0009968)
Children of negative regulation of signal transduction by receptor internalization (GO:0038011)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of insulin receptor signaling pathway by insulin receptor internalization (GO:0038014) [is_a relation] is_a  negative regulation of signal transduction by receptor internalization
negative regulation of Wnt signaling pathway by Wnt receptor internalization (GO:0038012) [is_a relation] is_a  negative regulation of signal transduction by receptor internalization
None.