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Term Information

Accession
GO:0036363
Name
transforming growth factor beta activation
Ontology
biological_process
Synonyms
L-TGF-beta activation, TGF-B activation, TGF-beta activation, TGFB activation, TGFbeta activation, latent TGF-beta activation
Alternate IDs
None
Definition
The release of transforming growth factor beta (TGF-beta) from its latent state. TGF-beta is secreted as part of a large latent complex (LLC) that is targeted to the extracellular matrix. Release of TGFbeta from its latent state is required for TGFbeta to bind to its receptors, and can occur by a variety of mechanisms. Source: PMID:9170210, GOC:bf, PMID:12482908, GOC:sl
Comment
None
History
See term history for GO:0036363 at QuickGO
Subset
None
Feedback
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Graph of GO:0036363

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Parents of transforming growth factor beta activation (GO:0036363)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
transforming growth factor beta activation [is_a relation] is_a  multicellular organismal process (GO:0032501)
transforming growth factor beta activation [BFO:0000050 relation] BFO:0000050  transforming growth factor beta production (GO:0071604)
Children of transforming growth factor beta activation (GO:0036363)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of transforming growth factor beta activation (GO:1901390) [RO:0002213 relation] RO:0002213  transforming growth factor beta activation
transforming growth factor beta2 activation (GO:0036365) [is_a relation] is_a  transforming growth factor beta activation
transforming growth factor beta3 activation (GO:0036366) [is_a relation] is_a  transforming growth factor beta activation
regulation of transforming growth factor beta activation (GO:1901388) [RO:0002211 relation] RO:0002211  transforming growth factor beta activation
transforming growth factor beta1 activation (GO:0036364) [is_a relation] is_a  transforming growth factor beta activation
negative regulation of transforming growth factor beta activation (GO:1901389) [RO:0002212 relation] RO:0002212  transforming growth factor beta activation
None.