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Term Information

Accession
GO:0035872
Name
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
Ontology
biological_process
Synonyms
NLR signaling pathway, nucleotide-binding domain leucine-rich repeat containing receptor signaling pathway, nucleotide-binding domain, leucine rich repeat containing receptor signal transduction, nucleotide-binding domain, leucine rich repeat containing receptor signal transduction pathway, nucleotide-binding domain, leucine rich repeat containing receptor signalling pathway, NOD-like receptor signaling pathway
Alternate IDs
None
Definition
A series of molecular signals generated as a consequence of a nucleotide-binding domain, leucine rich repeat containing receptor (NLR) binding to one of its physiological ligands. NLRs are cytoplasmic receptors defined by their tripartite domain architecture that contains: a variable C-terminus, a middle nucleotide-binding domain, and a LRR domain that is variable in the repeats composition and number. The NLR signaling pathway begins with binding of a ligand to a NLR receptor and ends with regulation of a downstream cellular process. Source: PMID:18280719, Reactome:168643, GOC:sj
Comment
None
History
See term history for GO:0035872 at QuickGO
Subset
None
Feedback
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Graph of GO:0035872

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Parents of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (GO:0035872)
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nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [is_a relation] is_a  intracellular receptor signaling pathway (GO:0030522)
Children of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (GO:0035872)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nucleotide-binding oligomerization domain containing signaling pathway (GO:0070423) [is_a relation] is_a  nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
None.