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Term Information

Accession
GO:0034976
Name
response to endoplasmic reticulum stress
Ontology
biological_process
Synonyms
ER stress response, cellular response to endoplasmic reticulum stress, response to ER stress
Alternate IDs
None
Definition
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen. Source: GOC:mah, GOC:cjm
Comment
None
History
See term history for GO:0034976 at QuickGO
Subset
None
Feedback
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Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Graph of GO:0034976

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Parents of response to endoplasmic reticulum stress (GO:0034976)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
response to endoplasmic reticulum stress [is_a relation] is_a  cellular response to stress (GO:0033554)
Children of response to endoplasmic reticulum stress (GO:0034976)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
response to manganese-induced endoplasmic reticulum stress (GO:1990737) [is_a relation] is_a  response to endoplasmic reticulum stress
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (GO:0070059) [is_a relation] is_a  response to endoplasmic reticulum stress
negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress (GO:1990441) [is_a relation] is_a  response to endoplasmic reticulum stress
negative regulation of response to endoplasmic reticulum stress (GO:1903573) [RO:0002212 relation] RO:0002212  response to endoplasmic reticulum stress
ER overload response (GO:0006983) [is_a relation] is_a  response to endoplasmic reticulum stress
ERAD pathway (GO:0036503) [is_a relation] is_a  response to endoplasmic reticulum stress
positive regulation of response to endoplasmic reticulum stress (GO:1905898) [RO:0002213 relation] RO:0002213  response to endoplasmic reticulum stress
endoplasmic reticulum stress-induced pre-emptive quality control (GO:0061857) [is_a relation] is_a  response to endoplasmic reticulum stress
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress (GO:1990440) [is_a relation] is_a  response to endoplasmic reticulum stress
regulation of response to endoplasmic reticulum stress (GO:1905897) [RO:0002211 relation] RO:0002211  response to endoplasmic reticulum stress
endoplasmic reticulum unfolded protein response (GO:0030968) [is_a relation] is_a  response to endoplasmic reticulum stress
regulation of translation in response to endoplasmic reticulum stress (GO:0036490) [BFO:0000050 relation] BFO:0000050  response to endoplasmic reticulum stress
None.